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European journal of Complementary and Alternative Medicine

Volume 13, Issue 1, 2026
Mcmed International
European journal of Complementary and Alternative Medicine
Issn
3117-5139 (Print), 3117-5147 (Online)
Frequency
bi-annual
Email
editorejcam@mcmed.us
Journal Home page
http://mcmed.us/journal/ejcam
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Abstract
Title
IN VITRO EVALUATION OF ANTIOXIDANT PROPERTIES OF CAESALPINIA PULCHERRIMA LEAF EXTRACT
Author
Dr. Siva Nageswara Rao Mekala1*, Dr. Ali Said Yussuf2
Email
sivanageshmekala@yahoo.com
keyword
Caesalpinia pulcherrima, antioxidant property, DPPH, L-ascorbic acid
Abstract
This study investigated the in vitro antioxidant capabilities of ethanolic leaf extracts from Caesalpinia pulcherrima, a medicinal plant traditionally employed in managing oxidative stress-related conditions. The research evaluated two key antioxidant parameters: DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity and hydroxyl radical scavenging capacity. Results demonstrated concentration-dependent antioxidant effects in both assays. For DPPH radical scavenging, the extract exhibited IC?? value of 0.27 mg/ml compared to 0.07 mg/ml for L-ascorbic acid (standard), indicating strong antioxidant potential. The hydroxyl radical scavenging assay revealed a concentration-dependent decrease in activity, with IC?? values of 0.14 mg/ml for the extract versus 1.06 mg/ml for the standard. These findings support the traditional use of C. pulcherrima in treating oxidative stress-associated disorders and suggest its potential as a natural alternative to synthetic antioxidants. Further investigations on active compound isolation, characterization, and safety evaluation are recommended
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