Acta Biomedica Scientia

CLINICOPATHOLOGICAL SPECTRUM OF LYMPH NODE LESIONS ENCOUNTERED ON FINE NEEDLE ASPIRATION CYTOLOGY IN SOUTH INDIA

Aravind Kumar M1, Rashmi Kunder

drpebyreddy@gmail.com

FNAC, Lymph node, Lymphadenopathy, Morphology, Metastatic lymphadenopathy, Tuberculous lymphadenitis.

Fine needle aspiration cytology (FNAC) is becoming preoperative method of choice for diagnosis and management of various lumps and lesions since few decades. It helps clinician to decide mode of treatment in most cases in both nonneoplastic and neoplastic disorders. As cervical, axillary and inguinal lymphadenopathies are commonly encountered clinical problems, in this study, we evaluated the utility of FNAC for assessment of lymphadenopathy. The present randomized Double blinded cross section Prospective study was conducted over 275 patients presenting with lymphadenopathy in the SLIMS, Pondicherry, central India over a period of one year and 4 months (September 2019 to December 2020 ), to evaluate the usefulness of FNAC as a diagnostic tool in the management of patients with superficial lymphadenopathy, distribution of various lesions among the different age groups, and to study cytological features of nonneoplastic & neoplastic lesions of enlarged lymph nodes by FNAC. Cervical lymph node was the most commonly involved group. Tuberculous lymphadenitis was most common lesion followed by reactive Hyperplasia, Metastatic carcinoma, Suppurative lymphadenitis, and non-Hodgkin’s lymphoma than Hodgkin's lymphoma. Incidence of metastatic carcinoma was high during & after 40 years of age & seen more common in males. Squamous cell carcinoma is the most common metastatic lesion. Most command site of metastasis in squamous cell carcinoma was cervical group of nodes where as in breast carcinoma axillary group of nodes. Fine needle aspiration is simple, rapid and cost-effective method to know the cause of lymphadenopathy and also a reliable method to categorize the cause of lymphadenopathy into reactive, inflammatory, metastatic, and lymphoproliferative, avoiding the necessity of biopsy